Lalla RV et al.
This is a prospective observational study, which aimed to evaluate the impact on periodontal parameters and the relationship between periodontal disease and dental caries in a patient population. More specifically, the patients had been diagnosed with head and neck squamous cell carcinoma or salivary gland cancer and underwent external beam radiotherapy. Their periodontal and cariological parameters were recorded during a 24-month period. The study included 533 patents at baseline, 414 at the 12-month visit, and 365 after 24 months.